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1

Neuroprotective and neurogenesis agent for treating bipolar II disorder: Add-on memantine to mood stabilizer works

Ru-Band Lu, Shiou-Lan Chen, Sheng-Yu Lee, Yun-Hsuan Chang, Shih-Heng Chen, Chun-Hsieh Chu, Nian-Sheng Tzeng, I Hui Lee, Po See Chen, Tzung Lieh Yeh, San-Yuan Huang, Yen Kuang Yang, Jau-Shyong Hong

Journal:

Medical Hypotheses

Year:

2012

Language:

english

File:

PDF, 67 KB

english, 2012

2

Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

Liya Qin, Xuefei Wu, Michelle L. Block, Yuxin Liu, George R. Breese, Jau-Shyong Hong, Darin J. Knapp, Fulton T. Crews

Journal:

Year:

2007

Language:

english

File:

PDF, 976 KB

english, 2007

3

Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology, and upregulation of ERK1/2, iNOS and sPLA2-IIA expression in astrocytes and microglia

Wenwen Sheng, Yijia Zong, Arwa Mohammad, Deepa Ajit, Jiankun Cui, Dongdong Han, Jennifer L Hamilton, Agnes Simonyi, Albert Y Sun, Zezong Gu, Jau-Shyong Hong, Gary A Weisman, Grace Y Sun

Journal:

Journal of Neuroinflammation

Year:

2011

Language:

english

File:

PDF, 1.67 MB

english, 2011

4

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

Block, Michelle L., Zecca, Luigi, Hong, Jau-Shyong

Journal:

Nature Reviews Neuroscience

Year:

2007

Language:

english

File:

PDF, 528 KB

english, 2007

5

Locus coeruleus neurons are most sensitive to chronic neuroinflammation-induced neurodegeneration

Wang, Qingshan, Oyarzabal, Esteban A., Song, Sheng, Wilson, Belinda, Santos, Janine H., Hong, Jau-Shyong

Journal:

Brain, Behavior, and Immunity

Year:

2020

Language:

english

File:

PDF, 2.82 MB

english, 2020

6

Neuroinflammation is a key player in Parkinson’s disease and a prime target for therapy

Li Qian, Patrick M. Flood, Jau-Shyong Hong

Journal:

Journal of Neural Transmission

Year:

2010

Language:

english

File:

PDF, 256 KB

english, 2010

7

Curcumin Protects Dopaminergic Neuron Against LPS Induced Neurotoxicity in Primary Rat Neuron/Glia Culture

Sufen Yang, Dan Zhang, Zhengqin Yang, Xiaoming Hu, Steven Qian, Jie Liu, Belinda Wilson, Michelle Block, Jau-Shyong Hong

Journal:

Neurochemical Research

Year:

2008

Language:

english

File:

PDF, 447 KB

english, 2008

8

Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression

Hui-Ming Gao, Jau-Shyong Hong

Journal:

Trends in Immunology

Year:

2008

Language:

english

File:

PDF, 446 KB

english, 2008

9

Role of oxidative stress in epileptic seizures

Eun-Joo Shin, Ji Hoon Jeong, Yoon Hee Chung, Won-Ki Kim, Kwang-Ho Ko, Jae-Hyung Bach, Jau-Shyong Hong, Yukio Yoneda, Hyoung-Chun Kim

Journal:

Neurochemistry International

Year:

2011

Language:

english

File:

PDF, 1.02 MB

english, 2011

10

Lithium and haloperidol differentially alter the dynorphin A (1–8) and enkephalin levels in the neurointermediate lobe of rat pituitary

Subbiah P. Sivam, Dan R. Smith, Koji Takeuchi, Jau-Shyong Hong

Journal:

Year:

1987

Language:

english

File:

PDF, 538 KB

english, 1987

11

Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson's Disease

Hui-Ming Gao, Feng Zhang, Hui Zhou, Wayneho Kam, Belinda Wilson and Jau-Shyong Hong

Journal:

Environmental Health Perspectives

Year:

2011

Language:

english

File:

PDF, 3.32 MB

english, 2011

12

PKCδ knockout mice are protected from para-methoxymethamphetamine-induced mitochondrial stress and associated neurotoxicity in the striatum of mice

Shin, Eun-Joo, Dang, Duy-Khanh, Tran, Hai-Quyen, Nam, Yunsung, Jeong, Ji Hoon, Lee, Young Hun, Park, Kyung Tae, Lee, Yong Sup, Jang, Choon-Gon, Hong, Jau-Shyong, Nabeshima, Toshitaka, Kim, Hyoung-Chun

Journal:

Neurochemistry International

Year:

2016

Language:

english

File:

PDF, 6.78 MB

english, 2016

13

NADPH oxidase-derived H 2 O 2 mediates the regulatory effects of microglia on astrogliosis in experimental models of Parkinson's disease

Hou, Liyan, Zhou, Xueying, Zhang, Cong, Wang, Ke, Liu, Xiaofang, Che, Yuning, Sun, Fuqiang, Li, Huihua, Wang, Qingshan, Zhang, Dan, Hong, Jau-Shyong

Journal:

Year:

2017

Language:

english

File:

PDF, 1.66 MB

english, 2017

14

Add-on Memantine Treatment for Bipolar II Disorder Comorbid with Alcohol Dependence: A 12-Week Follow-Up Study

Lee, Sheng-Yu, Wang, Tzu-Yun, Chen, Shiou-Lan, Chang, Yun-Hsuan, Chen, Po-See, Huang, San-Yuan, Tzeng, Nian-Sheng, Wang, Liang-Jen, Lee, I Hui, Chen, Kao Ching, Yang, Yen Kuang, Hong, Jau-Shyong, Lu,

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2018

Language:

english

File:

PDF, 433 KB

english, 2018

15

Interactive role of the toll-like receptor 4 and reactive oxygen species in LPS-induced microglia activation

Liya Qin, Guorong Li, Xun Qian, Yuxin Liu, Xuefei Wu, Bin Liu, Jau-Shyong Hong, Michelle L. Block

Journal:

Year:

2005

Language:

english

File:

PDF, 832 KB

english, 2005

16

Proteomic analysis of microglial contribution to mouse strain–dependent dopaminergic neurotoxicity

Patrick McLaughlin, Yong Zhou, Tracy Ma, Jun Liu, Wei Zhang, Jau-Shyong Hong, Monika Kovacs, Jing Zhang

Journal:

Year:

2006

Language:

english

File:

PDF, 3.08 MB

english, 2006

17

Microglial PHOX and Mac-1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha-synuclein

Wei Zhang, Shannon Dallas, Dan Zhang, Jian-Ping Guo, Hao Pang, Belinda Wilson, David S. Miller, Biao Chen, Wanqin Zhang, Patrick L. McGeer, Jau-Shyong Hong, Jing Zhang

Journal:

Year:

2007

Language:

english

File:

PDF, 412 KB

english, 2007

18

MAC1 mediates LPS-induced production of superoxide by microglia: The role of pattern recognition receptors in dopaminergic neurotoxicity

Zhong Pei, Hao Pang, Li Qian, Sufen Yang, Tonggauang Wang, Wei Zhang, Xeufei Wu, Shannon Dallas, Belinda Wilson, Jeffrey M. Reece, David S. Miller, Jau-Shyong Hong, Michelle L. Block

Journal:

Year:

2007

Language:

english

File:

PDF, 826 KB

english, 2007

19

β2 Adrenergic receptor activation induces microglial NADPH oxidase activation and dopaminergic neurotoxicity through an ERK-dependent/protein kinase A-independent pathway

Li Qian, Xiaoming Hu, Dan Zhang, Amanda Snyder, Hung-Ming Wu, Yachen Li, Belinda Wilson, Ru-Band Lu, Jau-Shyong Hong, Patrick M. Flood

Journal:

Year:

2009

Language:

english

File:

PDF, 347 KB

english, 2009

20

In utero bacterial endotoxin exposure causes loss of tyrosine hydroxylase neurons in the postnatal rat midbrain

ZaoDung Ling, Dave A. Gayle, Shang Yong Ma, Jack W. Lipton, Chong Wai Tong, Jau-Shyong Hong, Paul M. Carvey

Journal:

Movement Disorders

Year:

2002

Language:

english

File:

PDF, 222 KB

english, 2002

21

Study of hepatotoxicity of naltrexone in the treatment of alcoholism

Mao-Hsiung Yen, Huei-Chen Ko, Fu-In Tang, Ru-Band Lu, Jau-Shyong Hong

Journal:

Year:

2006

Language:

english

File:

PDF, 99 KB

english, 2006

22

In vitro model of glial scarring around neuroelectrodes chronically implanted in the CNS

Vadim S. Polikov, Michelle L. Block, Jean-Marc Fellous, Jau-Shyong Hong, W. Monty Reichert

Journal:

Year:

2006

Language:

english

File:

PDF, 647 KB

english, 2006

23

Control protocol for robust in vitro glial scar formation around microwires: Essential roles of bFGF and serum in gliosis

Vadim S. Polikov, Eric C. Su, Matthew A. Ball, Jau-Shyong Hong, William M. Reichert

Journal:

Journal of Neuroscience Methods

Year:

2009

Language:

english

File:

PDF, 683 KB

english, 2009

24

Soluble factor effects on glial cell reactivity at the surface of gel-coated microwires

Vadim S. Polikov, Jau-Shyong Hong, William M. Reichert

Journal:

Journal of Neuroscience Methods

Year:

2010

Language:

english

File:

PDF, 575 KB

english, 2010

25

Silymarin protects dopaminergic neurons against lipopolysaccharide-induced neurotoxicity by inhibiting microglia activation

Mei-Jen Wang, Wan-Wan Lin, Huan-Lian Chen, Ying-Hsin Chang, Hsio-Chung Ou, Jon-Son Kuo, Jau-Shyong Hong, Kee-Ching G. Jeng

Journal:

European Journal of Neuroscience

Year:

2002

Language:

english

File:

PDF, 409 KB

english, 2002

26

Expression of the Proenkephalin A Gene and [Met5]-Enkephalin Secretion Induced by Arachidonic Acid in Bovine Adrenal Medullary Chromaffin Cells: Involvement of Second Messengers

Hong W. Suh, Pearlie M. Hudson, Jau-Shyong Hong

Journal:

Journal of Neurochemistry

Year:

1995

Language:

english

File:

PDF, 629 KB

english, 1995

27

Long-Term Expression of Fos-Related Antigen and Transient Expression of ΔFosB Associated with Seizures in the Rat Hippocampus and Striatum

Guoying Bing, Wen Wang, Qiping Qi, Zhehui Feng, Pearlie Hudson, Lei Jin, Wanqin Zhang, Renjie Bing, Jau-Shyong Hong

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 1.13 MB

english, 1997

28

Neurons reduce glial responses to lipopolysaccharide (LPS) and prevent injury of microglial cells from over-activation by LPS

Raymond C. C. Chang, Wei Chen, Pearlie Hudson, Belinda Wilson, David S. K. Han, Jau-Shyong Hong

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 551 KB

english, 2001

29

Molecular consequences of activated microglia in the brain: overactivation induces apoptosis

Bin Liu, Kevin Wang, Hui-Ming Gao, Bhaskar Mandavilli, Jia-Yi Wang, Jau-Shyong Hong

Journal:

Journal of Neurochemistry

Year:

2001

Language:

english

File:

PDF, 547 KB

english, 2001

30

Microglial activation-mediated delayed and progressive degeneration of rat nigral dopaminergic neurons: relevance to Parkinson's disease

Hui-Ming Gao, Janwei Jiang, Belinda Wilson, Wanqin Zhang, Jau-Shyong Hong, Bin Liu

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 634 KB

english, 2002

31

Microglia enhance β-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species

Liya Qin, Yuxin Liu, Cynthia Cooper, Bin Liu, Belinda Wilson, Jau-Shyong Hong

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 313 KB

english, 2002

32

Role of reactive oxygen species in LPS-induced production of prostaglandin E2 in microglia

Tongguang Wang, Liya Qin, Bin Liu, Yuxin Liu, Belinda Wilson, Thomas E. Eling, Robert Langenbach, Seijiro Taniura, Jau-Shyong Hong

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 357 KB

english, 2004

33

Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity

Dan Zhang, Xiaoming Hu, Li Qian, Shih-Heng Chen, Hui Zhou, Belinda Wilson, David S Miller, Jau-Shyong Hong

Journal:

Journal of Neuroinflammation

Year:

2011

Language:

english

File:

PDF, 1.99 MB

english, 2011

34

Pharmacological modification of DDT-induced tremor and hyperthermia in rats: Distributional factors

David W. Herr, Jau-Shyong Hong, Paul Chen, Hugh A. Tilson, G. Jean Harry

Journal:

Psychopharmacology

Year:

1986

Language:

english

File:

PDF, 669 KB

english, 1986

35

Effect of acrylamide on neurotransmitter metabolism and neuropeptide levels in several brain regions and upon circulating hormones

S. Fatehyab Ali, Jau-Shyong Hong, William E. Wilson, Lynda L. Uphouse, Stephen C. Bondy

Journal:

Archives of Toxicology

Year:

1983

Language:

english

File:

PDF, 519 KB

english, 1983

36

Reduction of lipopolysaccharide-induced neurotoxicity in mouse mixed cortical neuron/glia cultures by ultralow concentrations of dynorphins

Ling-Yuan Kong, Gwang-Ho Jeohn, Pearlie M. Hudson, Lina Du, Bin Liu, Jau-Shyong Hong

Journal:

Journal of Biomedical Science

Year:

2000

Language:

english

File:

PDF, 1.10 MB

english, 2000

37

NeuroAIDS, Drug Abuse, and Inflammation: Building Collaborative Research Activities

Berman, Joan W., Carson, Monica J., Chang, Linda, Cox, Brian M., Fox, Howard S., Gonzalez, R. Gilberto, Hanson, Glen R., Hauser, Kurt F., Ho, Wen-Zhe, Hong, Jau-Shyong, Major, Eugene O., Maragos, Will

Journal:

Journal of Neuroimmune Pharmacology

Year:

2006

Language:

english

File:

PDF, 1.12 MB

english, 2006

38

Clozapine Protects Dopaminergic Neurons from Inflammation-Induced Damage by Inhibiting Microglial Overactivation

Hu, Xiaoming, Zhou, Hui, Zhang, Dan, Yang, Sufen, Qian, Li, Wu, Hung-Ming, Chen, Po-See, Wilson, Belinda, Gao, Hui-Ming, Lu, Ru-band, Hong, Jau-Shyong

Journal:

Journal of Neuroimmune Pharmacology

Year:

2012

Language:

english

File:

PDF, 657 KB

english, 2012

39

Astrogliosis in CNS Pathologies: Is There A Role for Microglia?

Dan Zhang, Xiaoming Hu, Li Qian, James P. O’Callaghan, Jau-Shyong Hong

Journal:

Molecular Neurobiology

Year:

2010

Language:

english

File:

PDF, 303 KB

english, 2010

40

Neuropsychopharmacological understanding for therapeutic application of morphinans

Eun-Joo Shin, Jau-Shyong Hong, Hyoung-Chun Kim

Journal:

Archives of Pharmacal Research

Year:

2010

Language:

english

File:

PDF, 495 KB

english, 2010

41

Role of Phagocyte Oxidase in UVA-Induced Oxidative Stress and Apoptosis in Keratinocytes

He, Yu-Ying, Huang, Jian-Li, Block, Michelle L, Hong, Jau-Shyong, Chignell, Colin F

Journal:

The Journal of Investigative Dermatology

Year:

2005

Language:

english

File:

PDF, 230 KB

english, 2005

42

Glycogen synthase kinase-3 negatively regulates anti-inflammatory interleukin-10 for lipopolysaccharide-induced iNOS/NO biosynthesis and RANTES production in microglial cells

Wei-Ching Huang, Yee-Shin Lin, Chi-Yun Wang, Cheng-Chieh Tsai, Hsiang-Chi Tseng, Chia-Ling Chen, Pei-Jung Lu, Po-See Chen, Li Qian, Jau-Shyong Hong, Chiou-Feng Lin

Journal:

Year:

2009

Language:

english

File:

PDF, 443 KB

english, 2009

43

Neonatal and Adult 6-Hydroxydopamine-Induced Lesions Differentially Alter Tachykinin and Enkephalin Gene Expression

Subbiah P. Sivam, George R. Breese, James E. Krause, T. Celeste Napier, Robert A. Mueller, Jau-Shyong Hong

Journal:

Journal of Neurochemistry

Year:

1987

Language:

english

File:

PDF, 1.27 MB

english, 1987

44

Long-Term Activation of Protein Kinase C by Angiotensin II in Cultured Bovine Adrenal Medullary Cells

Raimo K. Tuominen, Pearlie M. Hudson, Michael K. McMillian, Hong Ye, Michal K. Stachowiak, Jau-Shyong Hong

Journal:

Journal of Neurochemistry

Year:

1991

Language:

english

File:

PDF, 803 KB

english, 1991

45

Effects of [Sar1] Angiotensin II on Proenkephalin Gene Expression and Secretion of [Met5]Enkephalin in Bovine Adrenal Medullary Chromaffin Cells

Harold H. Suh, Eng-Chun Mar, Pearlie M. Hudson, Michael K. McMillian, Jau-Shyong Hong

Journal:

Journal of Neurochemistry

Year:

1992

Language:

english

File:

PDF, 700 KB

english, 1992

46

Role of Nitric Oxide in Inflammation-Mediated Neurodegeneration

BIN LIU, HUI-MING GAO, JIZ-YUH WANG, GWANG-HO JEOHN, CYNTHIA L. COOPER, JAU-SHYONG HONG

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 222 KB

english, 2002

47

Serum-Dependence of LPS-Induced Neurotoxicity in Rat Cortical Neurons

CYNTHIA L. COOPER, GWANG-HO JEOHN, PETER TOBIAS, JAU-SHYONG HONG

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 178 KB

english, 2002

48

Gö6976 Protects Mesencephalic Neurons from Lipopolysaccharide-Elicited Death by Inhibiting p38 MAP Kinase Phosphorylation

GWANG-HO JEOHN, CYNTHIA L. COOPER, KYUNG-JIN JANG, HYOUNG-CHUN KIM, JAU-SHYONG HONG

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 564 KB

english, 2002

49

Microglial NADPH Oxidase Mediates Leucine Enkephalin Dopaminergic Neuroprotection

LIYA QIN, YUXIN LIU, XUN QIAN, JAU-SHYONG HONG, MICHELLE L. BLOCK

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 10.18 MB

english, 2005

50

Role of Inflammation in the Pathogenesis of Parkinson's Disease : Models, Mechanisms, and Therapeutic Interventions

JAU-SHYONG HONG

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 36 KB

english, 2005

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